While the 49ers have won a fifth consecutive game, the Colts have now lost five straight. Here's the winners and losers from "Monday Night Football."

Brock Purdy threw five touchdown passes as the 49ers rolled to a 48-27 win over the Colts on Monday Night Football. Joe Montana was the last 49ers quarterback to throw five touchdowns when he did it in 1990.

There are three AFC teams that will have full support for the 49ers when they face the Colts on Monday night. Three AFC teams will be in full support of the San Francisco 49ers when they take on the Indianapolis Colts on Monday night.

Heading into Week 15's Monday Night Football matchup against the Pittsburgh Steelers, the Dolphins will face a Steelers team missing T.J. Watt and a sick Jaylen Warren. But it won't be easy for Tua Tagovailoa and the Dolphins as the Steelers are at home.

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the highlights.