Using a powerful single-molecule imaging method they developed, a Broad Institute research team has unveiled a dynamic view ...
A single molecule that tricks its way into fat cells by mimicking a gut hormone, then releases a second drug once inside, has ...
A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled receptors in living cells actually respond to activating substances. The ...
Adhesion G protein-coupled receptors have a large extracellular region (shown in green and orange) that extends into space outside the cell. Almost 35% of drugs approved by the Food and Drug ...
Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...
Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...
An international team of researchers has identified an East African bat coronavirus capable of entering human cells. While the virus—Cardioderma cor coronavirus (CcCoV) KY43, or CcCoV-KY43—can bind to ...