San Francisco 49ers RB Christian McCaffrey racked up 114 total scrimmage yards and two receiving touchdowns Sunday vs. the Philadelphia Eagles in Wild Card Weekend of the 2025 NFL season.

Watch highlights of San Francisco 49ers running back Christian McCaffrey from the 2025 NFL season. San Francisco 49ers S ...

Watch the best plays from San Francisco 49ers running back Christian McCaffrey's 146-yard game against the Indianapolis Colts in Week 16 of the 2025 NFL season. Watch the best plays from San Francisco ...

After a 2024 campaign derailed by injuries, an Achilles setback in training camp and a season-ending knee injury in Week 13, ...

The Seattle Seahawks rendered 49ers star Christian McCaffrey a non-factor again in San Francisco's 41-6 loss on Saturday at ...