While peripheral artery disease symptoms are most common in upright positions, it’s possible for more severe cases to cause leg pain at night. The most commonly reported symptom of peripheral artery ...

Leg pain affects nearly everyone at some point, ranging from routine muscle soreness after exercise to the occasional cramp that resolves quickly. This commonplace nature makes it easy to dismiss leg ...

Sometimes, aches and pains get dismissed as a normal part of getting older. In the case of peripheral artery disease, or PAD, those pains can be signs of a serious problem. Subscribe to our newsletter ...

Sciatica can cause pain, tingling, or weakness in the leg due to compressed spinal nerve roots. Arthritis, including ...

DEAR MAYO CLINIC: I'm 52 years old and enjoy long walks with my husband and our dog. I recently started to experience pain in my left calf during our walks. The leg pain goes away when I rest. Because ...

Discover the everyday habits that may be quietly causing your back and neck pain—and the simple changes that can make a big ...

Everyone deals with random aches and pains from time to time. But when it comes to a sharp pain in the front of your thigh, there are several possible causes. The pain may be due to muscle injury, ...

Leg pain in children is typically caused by growing pains, muscle spasms, and strained muscles, all of which can be treated at home. However, certain signs may indicate something more serious is going ...

Lower spine pain can develop due to sprains and strains of muscles or changes to the discs in the lower back. Conditions that affect the facet joints of the vertebrae may also cause lower spine pain.

DEAR MAYO CLINIC: I'm 52 years old and enjoy long walks with my husband and our dog. I recently started to experience pain in my left calf during our walks. The pain goes away when I rest. Because I ...