Chimeric antigen receptor T cell therapy reduces vaccine immunity, with many patients lacking seroprotection despite stable antibody levels.

The use of a monoclonal antibody that reduced circulating IgG levels, led to a decrease in preexisting neutralizing antibodies (NAbs) to adeno-associated virus (AAV). The study, which showed that this ...

Disparities in multiple myeloma: A global perspective on drug toxicity trends. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include a full text ...

In a recent review published in Pathogens, researchers discussed studies that explored T-cell immunity induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus ...

Combining Homologous Recombination-Deficient Testing and Functional RAD51 Analysis Enhances the Prediction of Poly(ADP-Ribose) Polymerase Inhibitor Sensitivity We analyzed RNA-seq data of 113 patients ...

Killer cell immunoglobulin-like receptor 3DL3 (KIR3DL3) is a member of the killer cell Ig-like (KIR) receptor family. When KIR3DL3 is expressed on T and natural killer (NK) cells in the tumor ...

In a recent study posted to the bioRxiv* preprint server, researchers report that sublineages of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant effectively escape ...

Immune checkpoint inhibitors have reshaped cancer treatment over the past decade, but the same immune activation that shrinks tumors can also turn against healthy tissue, including the brain. A ...