Within 4 hours of the first dose, defecation occurred in 48% of methylnaltrexone patients and in 15% of the placebo patients. Constipation is common among people who take opioids chronically.

Researchers at University of Tsukuba revealed that administering naldemedine, which is a constipation medication, alongside ...

Rizmoic is a once-daily 200-microgram oral tablet for the treatment of opioid induced constipation (OIC) in adult patients previously treated with a laxative. Shionogi received EU marketing ...

Goodman ML, Wilkinson S: Laxatives for the management of constipation ... metoclopramide 10 mg t.d.s. p.o. in the treatment of opioid-induced nausea and emesis in cancer patients.

Daniel Ghinn examines the social media conversations around an advertisement for opioid-induced constipation that was aired during the final of the hugely popular American football championship in ...

as the second annual Opioid-Induced Constipation (OIC) Awareness Day. This important day is dedicated to bringing awareness to a commonly-overlooked side effect of opioids. By raising awareness ...