Men with elevated blood levels of the amino acid tyrosine lost roughly one year of life on average, according to a large ...

Obesity is a risk factor for several cancers, but the mechanistic basis is poorly understood. We sought to identify circulating metabolites mediating the effect of obesity on the risk of eight common ...

Lymphoma is a malignancy arising from the lymphatic system and can be classified into non-Hodgkin’s lymphoma (NHL) and Hodgkin’s lymphoma (HL). According to the latest findings from GLOBOCAN 2020, ...

Traditional epidemiological studies have identified numerous potential risk factors, but observational studies have struggled to establish causal links due to confounding factors and reverse causation ...

The schematic illustrates the comprehensive pipeline for Mendelian randomization analysis, starting with multi-omics data inputs from GWAS, eQTL, and pQTL studies, sourced from major databases such as ...

Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease. This technique uses genetic variations as "natural experiments" to reveal ...

A new study identifying 56 non-clinical risk factors associated with sudden cardiac arrest (SCA), spanning lifestyle, physical measures, psychosocial factors, socioeconomic status, and the local ...

Imagine if a doctor could look at your DNA and predict not just your disease risk, but also which foods you're drawn to – and ...