A clinical trial of an experimental drug for treatment-resistant major depression finds that modulation of the endogenous opioid system may improve the effectiveness of drugs that target the action of ...

September 12, 2012 — A centralized prescription network that gives real-time access to data on filled prescriptions for individual patients can reduce inappropriately filled prescriptions for opioids ...

After Maryland became one of the top five states for opioid-related deaths in 2017, Annapolis-based Anne Arundel Health System created a formula to measure opioid overprescribing within its EHR system ...

Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and ...

A new Scientific Statement released today by the Endocrine Society highlights research gaps associated with the negative effects of opioid use on the endocrine system. The use and misuse of opioids ...

The morphinelike compound McDougall refers to is known as endomorphin 1, and his team studied whether peripheral administration of this endogenous ¿-opioid peptide could reduce knee joint pain.

How does your doctor actually prescribe opioid medication? Why is it hard to get a refill? What are the best solutions to ...

Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while stripping away the worst dangers of addiction and overdose. Instead of tweaking ...

Adolescents in the US face significant barriers to accessing effective drug treatment, with only 31% of children ages 12-17 ...

A drug called buprenorphine may be the best tool doctors have to fight the fentanyl crisis. Why hasn’t it been more widely adopted? A dose of buprenorphine, an opioid that can help treat addiction to ...