Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...

Amylin, a hormone that controls appetite and blood sugar by activating three different receptors in the brain, could be the basis for the next blockbuster obesity drugs. A University of Oklahoma study ...

Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually ...

The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have now discovered ...

The bacterium Pseudomonas aeruginosa is the leading cause of hospital-acquired infections. The pathogen is resistant to many antibiotics so treating those infections, particularly in patients with ...

Opioid agonist/antagonist has a big impact in phase IIb trial ...

For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major ...

Psilocybin—the psychedelic compound that occurs naturally in certain "magic" mushroom species—has been shown in trials to provide long-term treatment for depression and anxiety. But the chemical's ...

Oct. 28 -- TUESDAY, Oct. 27 (HealthDay News) -- Some common herbicides and cholesterol drugs block a nutrient-sensing receptor known as T1R3, researchers report. "Compounds that either activate or ...