The San Francisco 49ers offensive line's new starting left guard may have been announced inadvertently by one of the team's ...

Detroit Lions quarterback Jared Goff (16) is sacked by San Francisco 49ers defensive end Nick Bosa (97) during the first half at Levi's Stadium in Santa Clara, Calif. on Monday, Dec. 30, 2024.

Earlier this offseason, the San Francisco 49ers released and re-signed Kyle Juszczyk, who is now talking about how that ...

Detroit Lions quarterback Jared Goff (16) throws a pass during the first half of an NFL football game against the San Francisco 49ers, Monday, Dec. 30, 2024, in Santa Clara, Calif. (AP Photo ...

Detroit Lions (13-2) at San Francisco 49ers (6-9). The coaches: Lions — Dan Campbell (42-35-1 overall, 37-28-1 with Lions); 49ers — Kyle Shanahan (70-60 overall, 70-60 with 49ers).. Last game ...

Detroit Lions vs. San Francisco 49ers: Expert Predictions. Some experts predict the Lions will dominate the 49ers, with projected scores like 26-16, 28-20, and even 31-20.

A top NFL ESPN analyst has handed out a surprisingly low ranking to San Francisco 49ers star RB Christian McCaffrey.

Jordan Mendoza: Lions 28, 49ers 20 Even against a solid defense like San Francisco, Detroit should find some holes that lead to scores. The Lions keep control of the NFC.

The San Francisco 49ers had a rough offseason after a down year in 2024, but there are plenty of reasons to believe they'll ...

San Francisco 49ers quarterback Brock Purdy began his career as the fourth quarterback on the depth chart, but his teammates wanted to see him play.

The NFL season is still nearly two months away, but a handful of bets for Week 1 are already gaining traction among fans.

LOS ANGELES (AP) — San Francisco 49ers player Deommodore Lenoir was arrested in Los Angeles on a charge of obstructing law ...