The process of 'translation' in protein synthesis involves formation of a peptide bond between two amino acids that are attached to two distinct transfer RNAs (tRNAs). For long, scientists have been ...

Peptides are often chemically synthesized by processes such as solid-phase synthesis, 12 ring-opening polymerization of N-carboxyanhydrides 13 and recombinant synthesis. 14, 15 Although these methods ...

A peptide bond is a chemical bond formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule, releasing a molecule of water (H2O). This is a ...

Nature makes amide bonds—the key linkages that string together amino acids in a polypeptide—like a knitting whiz. The ribosome in Escherichia coli bacteria, for example, can make eight amide bonds in ...

Over 100 years have passed since the first attempts to form amide bonds using simple starting materials. Despite this, great efforts are still being invested to develop new methods of efficiently ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 51, No. 6 (Jun. 15, 1964), pp. 1291-1299 (9 pages) ...

Manufacturers Look for an Edge to Increase Purity and Lower Costs as Demand Grows The environmental impact of large-scale peptide production can be staggering. In his presentation at the “Avakado ...

The Peptide-ExplorerLT ™ is designed for scientists who need to optimize and explore linear peptide synthesis. The product is a high-spec flow chemistry system that uses continuous flow. The product ...

Automation and advances in solid- and liquid-phase approaches are but a few factors driving costs down, according to this article from our July 1 issue. The continued strong demand for peptides as ...

Peptides have emerged as indispensable tools in modern drug discovery, playing a central role in areas such as oncology, metabolic disorders, targeted delivery, and protein–protein interaction ...

The genetic information stored in DNA is “decoded” to form proteins via the process of translation. This involves the formation of peptide bonds between amino acids bound to transfer RNA (tRNA) ...