San Francisco 49ers head coach Kyle Shanahan discussed the team's injury status, highlighted the offensive momentum led by QB Mac Jones and RB Christian McCaffrey, and shared how the 49ers are prepari

Christian McCaffrey speaks out on the San Francisco 49ers’ mounting injury challenges after losing to the Houston Texans.

San Francisco 49ers running back Christian McCaffrey is on pace for another historic season, potentially etching his name alongside some of the NFL's all-time greats.

Niners' running back Christian McCaffrey leads the NFL in touches and scrimmage yards this season. San Francisco's season might hinge on him remaining healthy.

Christian McCaffrey and the San Francisco 49ers hope to get back on track running the ball against the New York Giants and their 30th-ranked rush defense.

SANTA CLARA — After a frustrating, injury-plagued 2024 NFL season, Christian McCaffrey is ready to move forward -- both healthy and happy. The All-Pro ball carrier spoke to local Bay Area media Tuesday and shared an update on his physical health.

San Francisco 49ers TE George Kittle came forward to defend his friend and teammate, Christian McCaffrey, amid the backlash for his underwhelming performance this season.

One day after popping up on the injury report on Thursday, San Francisco 49ers running back Christian McCaffrey has spoken about his issue. McCaffrey was listed as limited on Thursday's injury report with a calf injury, which is especially concerning given ...

Christian McCaffrey delivers blunt comments to Brian Robinson Jr. following the San Francisco 49ers’ victory over the New York Giants.

San Francisco 49ers running back Christian McCaffrey (23) stiff-arms New York Giants cornerback Andru Phillips (22) during the third quarter of an NFL football game, Sunday, Nov. 2, 2025, in East Rutherford, N.J. Credit: AP/Frank Franklin II