New research suggests pain is not a simple signal of injury but a process that unfolds across nerves, spinal cord, and brain.

Muse Treatment Alcohol & Drug Rehab Los Angeles has published a new educational resource that explains how opioid receptors ...

Scientists are developing a "sponge" that can soak up pain signals in the body before they reach the brain, potentially ...

A new study finds that an increasing number of surgeries — and the painkillers that follow — could derail recovery for those who once misused opioids.

The new method is designed to focus specifically on pain-related signals, without interfering with normal activity in other parts of the brain. A new preclinical study has identified a gene therapy ap ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

A clinical trial at Brown University Health to treat chronic low back pain with a one-time, non-surgical injection treatment ...

Nocion Therapeutics, Inc. a biopharmaceutical company developing novel small molecule therapies that selectively silence activated sensory neurons, today announced that preclinical data supporting the ...

Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while stripping away the worst dangers of addiction and overdose. Instead of tweaking ...

A neural circuit hidden in an understudied region of the brain plays a critical role in turning temporary pain into pain that can last months or years, according to new University of Colorado Boulder ...

Chronic pain affects more than 50 million Americans, yet for decades, treatment options for pain that persists in the absence ...