eLife

PTEN restrains SHH medulloblastma growth through cell autonomous and nonautonomous mechanisms

PTEN mutations are enriched in the SHH-1 subtype that has the lowest survival rate. Widespread heterozygous loss of Pten in two SHH-MB mouse models increases penetrance and excellerates onset of ...
C&EN

Maternal Exposure to Combined Cadmium and Polystyrene Nanoplastics Induces Offspring Testicular Dysplasia via Mitochondrial Reactive Oxygen Species Overactivating the ...

The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330000, China ...
PNAS

Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway–dependent Rho/ROCK signaling

We are grateful to members of the Prives and Kaufman labs for helpful discussions and advice. Ella Freulich is thanked for expert technical assistance in preparing laboratory reagents and cell culture ...
New York Post

James Comey’s defense attorney may have a conflict of interest, feds claim, signaling they may seek to boot him

The lawyer defending James Comey against charges he lied to Congress might need to be kicked off the case over his alleged involvement in the same media leaks during the first Trump administration ...
International

U.S. Foreclosure Filings Jump 17 Percent Annually in Q3 Signaling Borrower Strain

Foreclosure activity in the U.S. continued its upward climb in the third quarter of 2025, suggesting that pockets of borrower distress may be emerging. New data from ATTOM's Q3 2025 U.S. Foreclosure ...