Reliable methodology to selectively install a peptide isostere, such as a reduced amide bond, is expected to facilitate the synthesis of valuable peptide-based inhibitors and to aid in studies of ...

Nature makes amide bonds—the key linkages that string together amino acids in a polypeptide—like a knitting whiz. The ribosome in Escherichia coli bacteria, for example, can make eight amide bonds in ...

The process of 'translation' in protein synthesis involves formation of a peptide bond between two amino acids that are attached to two distinct transfer RNAs (tRNAs). For long, scientists have been ...

A peptide bond is a chemical bond formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule, releasing a molecule of water (H2O). This is a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 51, No. 6 (Jun. 15, 1964), pp. 1291-1299 (9 pages) ...

Peptide synthesis is an expanding component of the biotechnology industry. With advances in the technology of linking amino acids together, the cost of synthetic peptides has dropped dramatically, ...

A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery ...

Manufacturers Look for an Edge to Increase Purity and Lower Costs as Demand Grows The environmental impact of large-scale peptide production can be staggering. In his presentation at the “Avakado ...

The genetic information stored in DNA is “decoded” to form proteins via the process of translation. This involves the formation of peptide bonds between amino acids bound to transfer RNA (tRNA) ...