New drugs that target "zombie" tuberculosis (TB) cells are now a step closer, thanks to a new study led by the University of ...

Feb. 16, 2021 — Researchers may have found a new pathway to treat and control tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb). Using single-cell RNA sequencing ...

Moreover, the Aldridge Lab used time-lapse, single-cell imaging to discover that the two poles of Mycobacterium tuberculosis grow at different rates. This means that one end will end up growing faster ...

Using precise molecular techniques, including single-cell RNA sequencing, the team showed that this process is mediated in part by the effects of CD4 T cells on CD8 T cells – another subset of ...

The body's first line of defense against tuberculosis (TB) involves immune cells that suppress lung inflammation instead of activating it, report University of Pittsburgh and the Ragon Institute ...

Current tuberculosis infection tests struggle to detect the disease in those with HIV. A common co-infection, HIV can hide TB ...

More information: Nezar Mehanna et al, CD8α marks a Mycobacterium tuberculosis-reactive human NK cell population with high activation potential, Scientific Reports (2025). DOI: 10.1038/s41598-025 ...

Some tuberculosis researchers had hypothesized that the bacterial cells shed ManLAM once inside a host cell, and that those free glycans then interact with the host immune system. However, the MIT ...

Tuberculosis is the world's leading infectious cause of death, killing more than one million people each year. When the antibiotic bedaquiline was introduced in 2012, it was the first new ...

The red-cell count was 3,260,000, with a hemoglobin of 9 gm. (58 per cent), and the white-cell count 5640, with 60 per cent neutrophils, 12 per cent large lymphocytes, 24 per cent small ...

Legislation that aims to prevent preventable deaths from tuberculosis infection is one step closer to becoming law.