During the San Francisco 49ers 35-10 loss to the Buffalo Bills on Sunday night, superstar running back Christian McCaffrey ...

The San Francisco 49ers suffered another disappointing loss on Sunday night as they took on the Buffalo Bills on the road in ...

The San Francisco 49ers endured another disheartening loss Sunday night, falling to the Buffalo Bills and dropping to 5-7 on ...

According to Adam Schefter, it's anticipated that LB Azeez Al-Shaair will face a suspension for the hit he put on Jaguars QB ...

From one coast to another, a former Washington Commanders first-round pick has signed with a new club after being waived by ...

Despite Trevor Lawrence telling fans he's home and "feeling better," ESPN's Adam Schefter had a troubling update to share ...

The Los Angeles Rams' bitter rival suffered yet another devastating injury during their Week 13 road loss against the Buffalo ...

The Houston Texans will likely be without Azeez Al-Shaair moving forward following the linebacker's ruthless hit on ...

New Orleans Saints tight end Taysom Hill is out for the season with a knee injury, per ESPN's Adam Schefter. Tests confirmed ...

A Monday morning recap of the fantasy football relevant injuries from Week 13 of the NFL season by our Injury Expert Adam ...

With Christian McCaffrey (knee) and Jordan Mason (ankle) placed on injured reserve Monday, Guerendo is expected to take over as the 49ers' starting running back, Adam Schefter of ESPN reports.

The 49ers take on the Bills on "Sunday Night Football" in Week 13. Here's the latest on if QB Brock Purdy will be available ...