A microglia replacement approach demonstrates that brain macrophages with patient mutations from Aicardi–Goutières syndrome, a genetic, brain predominant interferonopathy, are sufficient to drive ...
A research team has developed a way to produce a subset of highly specialised brain neurons that centrally degenerate in motor neuron disease and are damaged in spinal cord injury, laying foundations ...
Developmental electrophysiological adaptations and heat-sensitive proteins, such as TRPV3, in cortical excitatory neurons help maintain stable activity levels when brain temperature rises by 2–3°C ...
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