High-Dose Flu Shot Beats Standard Dose in At-Risk Patients The high-dose influenza vaccine elicits stronger immune responses in immunocompromised patients while maintaining a safety profile similar to ...

Jun 27 2025 This Week in Cardiology FDA approves triple-drug polypill, a change of opinion, a deep dive into invasive pulmonary embolism therapies, heart disease trends, and diabetes care is on fire ...

Conclusions We suggest that IL-1α release from infundibular keratinocyte in response to P. acnes- mediated TLR activation is an important step in the complex natural history of the acne lesion (Figure ...

Optimization of Settings Biventricular pacing has two primary (electrical) effects on the heart; the first effect is the change in atrioventricular (A-V) interval, which influences the timing of ...

Tramadol is a synthetic centrally acting analgesic that binds weakly to µ-receptors. At the same time, it stimulates descendent inhibitory pathways in the spinal cord by enhancing release and ...

Other Investigations The number of commercially available investigations is growing rapidly. Human beta-defensin-2 (HBD2) is a protein produced by intestinal epithelial cells (Paneth cells) on contact ...

Discussion This analysis found strong evidence of PCV benefit against both clinical and radiologically confirmed pneumonia in the age group targeted for vaccination using 2+1, 3+0 and 3+1 schedules.

One year after presentation in the US, the patient entered into an observational study to evaluate risk factors associated with the development of subclinical atherosclerosis in patients with SLE. At ...