Niners' running back Christian McCaffrey leads the NFL in touches and scrimmage yards this season. San Francisco's season might hinge on him remaining healthy.

The Rams chase redemption and first place in the NFC West as they face the battered 49ers in a high-stakes Week 10 rematch.

San Francisco 49ers DL Clelin Ferrell, T Trent Williams, and DL Keion White spoke on maintaining composure, embracing the ...

San Francisco 49ers running back Christian McCaffrey is on pace for another historic season, potentially etching his name ...

San Francisco 49ers running back Christian McCaffrey (23) stiff-arms New York Giants cornerback Andru Phillips (22) during ...

After finding the end zone one time on the ground and rushing for 106 yards on 28 carries in his last game, Christian ...

According to FanDuel Sportsbook, Indianapolis Colts running back Jonathan Taylor is the clear favorite (-135) to win NFL ...

49ers bold predictions for Week 10 clash with Rams: McCaffrey 150+ yards, Stafford turnovers, San Francisco upset victory.

Colin Cowherd on Kyle Shanahan: “My Coach of the Year is Kyle Shanahan. He’s winning with peanut brittle, baling wire and ...

Exiting their bye week, the Los Angeles Rams dominated the New Orleans Saints in a game that was never in doubt for Sean ...

Despite a wave of injuries to key position groups, San Francisco has persevered and is right in the thick of an ...

The San Francisco 49ers have decided against making major trades to strengthen their injury-depleted roster. Despite a 6-3 ...