Bacille Calmette-Guérin revaccination shows no efficacy in preventing sustained Mycobacterium tuberculosis infection compared with placebo in adolescents in a phase 2b study.

Once thought to have originated in cows and spread through dust, the surprising evolutionary story of tuberculosis reveals ...

Feb. 16, 2021 — Researchers may have found a new pathway to treat and control tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb). Using single-cell RNA sequencing ...

Feb. 16, 2021 — Researchers may have found a new pathway to treat and control tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb). Using single-cell RNA sequencing ...

Current tuberculosis infection tests struggle to detect the disease in those with HIV. A common co-infection, HIV can hide TB ...

The body's first line of defense against tuberculosis (TB) involves immune cells that suppress lung inflammation instead of activating it, report University of Pittsburgh and the Ragon Institute ...

More information: Nezar Mehanna et al, CD8α marks a Mycobacterium tuberculosis-reactive human NK cell population with high activation potential, Scientific Reports (2025). DOI: 10.1038/s41598-025 ...

T cells, another important white blood cell of the immune system, also play a part, and specifically CD4+, or helper T cells, that can initiate immune responses.

Legislation that aims to prevent preventable deaths from tuberculosis infection is one step closer to becoming law.

Moreover, the Aldridge Lab used time-lapse, single-cell imaging to discover that the two poles of Mycobacterium tuberculosis grow at different rates. This means that one end will end up growing faster ...

Some tuberculosis researchers had hypothesized that the bacterial cells shed ManLAM once inside a host cell, and that those free glycans then interact with the host immune system. However, the MIT ...

The body's first line of defense against tuberculosis (TB) involves immune cells that suppress lung inflammation instead of activating it, report University of Pittsburgh and the Ragon Institute ...