Hurricane Melissa struck the western part of Jamaica the hardest, leaving widespread destruction, officials said. Black River Hospital on the southwest side of the island has been devastated and several other hospitals suffered damage, Desmond McKenzie, the minister of Local Government and Community Development, said.

Cuba suffered “significant damage” after Melissa made landfall there Wednesday morning as a Category 3 hurricane.

Forecasters say the Category 5 storm is likely to cause “catastrophic” flooding, landslides and widespread damage, and the Red Cross warns that up to 1.5 million people may be directly affected.