Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Since returning from an Achilles tendinitis issue, Christian McCaffrey has dominated the San Francisco 49ers' backfield, playing 88% of the offensive snaps. In contrast, Jordan Mason has seen just 8% ...

Isaac Guerendo didn’t start in college until his final game.. He starts at running back for the 49ers Sunday against Chicago.

HC Kyle Shanahan provided updates about LB Dre Greenlaw, S Talanoa Hufanga, and why he’s excited about Isaac Guerendo’s ...

It’s back to the grind for a weary 49ers team attempting to hold onto their rapidly waning playoff dreams. They’ll face a ...

Dealing with injuries to Christian McCaffrey and Jordan Mason at running back, the 49ers have made a move at the position.

Week 13 was a very nice and impressive week for quarterbacks. Here are the grades for all 32 NFL teams’ quarterbacks after ...

The San Francisco 49ers could say goodbye to RB Jordan Mason, one of their most productive offensive players, in the near ...

Mason (ankle) did not practice Wednesday, Matt Barrows of The Athletic reports. When he spoke with the media Monday, coach Kyle Shanahan said Mason would be going to injured reserve with a high-ankle ...

Former Wisconsin Badgers running back Isaac Guerendo is in line to serve as the San Francisco 49ers starting running back for ...

The Thanksgiving holiday was make or break for a lot of teams in the NFL. Some teams separated themselves with respect to ...

The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...