San Francisco 49ers offensive lineman Trent Williams was sidelined Sunday against the Buffalo Bills due to an ankle injury.

Parts of the Great Lakes region are seeing new snow and face the prospect of even more this week after U.S. travelers battled ...

Fans are praying for San Francisco 49ers offensive tackle Trent Williams after his wife revealed their newborn son had passed ...

The San Francisco 49ers endured another disheartening loss Sunday night, falling to the Buffalo Bills and dropping to 5-7 on ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

With the win, the Bills improved to 10-2 for the first time since 1991 and are just the fourth team since the turn of the ...

The San Francisco 49ers suffered another disappointing loss on Sunday night as they took on the Buffalo Bills on the road in ...

The Buffalo Bills hammered the San Francisco 49ers 35-10 in a snow-filled rout led by Josh Allen’s 4 TDs. Colin Cowherd ...

The Buffalo Bills are now slightly favored over the Kansas City Chiefs to finish as the No. 1 seed in the AFC.

Buffalo Bills quarterback Josh Allen enhanced his MVP credentials with a win over the San Francisco 49ers.

The team that was supposed take a backward step or even two after saying goodbye to several key players in the offseason has ...

After news of Josh Allen and Hailee Steinfeld’s engagement, NBC sideline reporter Melissa Stark dropped some tidbits about ...