Without Nico Collins or Christian Kirk in the lineup, quarterback C.J. Stroud logged a completion to nine different pass-catchers on the day for over 300 yards and two touchdowns. It came out to be one of his and the offense's best performances of the season so far, and of course, led to a winning effort.

Houston coach DeMeco Ryans had high praise for C.J. Stroud after his performance in Sunday’s win over San Francisco. “One of his best games ever,” Ryans said.

C.J. Stroud delivered in a big way for the Houston Texans against the San Francisco 49ers and spoke candidly afterward.

Oct 20, 2025; Seattle, Washington, USA; Houston Texans quarterback C.J. Stroud (7) runs onto the field for warmups prior to the game against the Seattle Seahawks at Lumen Field. Mandatory Credit: Kevin Ng-Imagn Images / Kevin Ng-Imagn Images

The Houston Texans (3-4) were triumphant over the San Francisco 49ers (5-3), winning 26-15. It is Houston’s first win this season over a team with a winning record, and an important step forward.

Instead of having to settle for another field goal, C.J, Stroud and Xavier Hutchinson hooked up to put the 49ers in a deeper hole.

After the Texans beat the 49ers, DeMeco Ryans would shout out quarterback C.J. Stroud, citing one of his best games ever.