Belém, often called Belém of Pará, is the capital and largest city of the state of Pará in the north of Brazil. It is the gateway to the Amazon River with a busy port, airport, and bus/coach station. Belém lies approximately 100 km upriver from the Atlantic Ocean, on the Pará River, which is part of the greater Amazon River system, separated from the larger part of the Amazon delta by Ilha de Marajó. With an estimated population of 1,303,403 people — or 2,491,052, considering its metropolitan area — it is the 12th most populous city in Brazil, as well as the 16th by economic relevance. It is the second largest in the North Region, second only to Manaus, in the state of Amazonas.