George M. Solomon, M.D., assistant professor of medicine and director of the adult CF program at UAB - The University of Alabama at Birmingham, updates us on new developments in CFTR modulators that will help people living with cystic fibrosis who have a wider range of CFTR mutations. To learn more about drugs in development, visit our pipeline: http://on.cff.org/pipeline | Cystic Fibrosis Foundation
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George M. Solomon, M.D., assistant professor of medicine and directo…
122.5K viewsAug 16, 2017
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Watch this animation to understand how CFTR modulators work for people with F508del mutations. To learn more about drugs in development to restore CFTR function, visit our drug development pipeline: http://on.cff.org/pipeline | Cystic Fibrosis Foundation
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Watch this animation to understand how CFTR modulators work for pe…
135.5K viewsApr 20, 2017
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Until recently, only about 60 percent of the cystic fibrosis population was eligible for CFTR modulator therapy. Now, with the approval of Trikafta, a triple-combination CFTR modulator therapy, more than 90 percent of people with CF could eventually have a highly effective therapy for the underlying cause of their disease. Alex Gifford, MD, an associate professor of medicine and the director of the adult CF program at Dartmouth-Hitchcock, discusses clinical trials that study the effects of CFTR
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Until recently, only about 60 percent of the cystic fibrosis population w…
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Since the introduction of CFTR modulators, pregnancies in women with cystic fibrosis have increased significantly. When Chelsea Jones heard about more women with CF getting pregnant while taking Trikafta, it renewed her hope for having children. Chelsea and her fiancé were overjoyed when she became pregnant with their first daughter, and the couple now has two girls. | Cystic Fibrosis Foundation
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Since the introduction of CFTR modulators, pregnancies in wome…
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CFTR Modulator Therapies
CFTR Modulator Therapies
Aug 13, 2024
cff.org
Types of CFTR Mutations
Types of CFTR Mutations
Oct 16, 2024
cff.org
Since 2012 when the first CFTR modulator, Kalydeco, was approved, modulator therapy has transformed cystic fibrosis care. By the end of 2024, 24,524 people with CF in the United States were prescribed Trikafta, according to data from the Patient Registry. However, 7.3% of people with CF were still not eligible for any CFTR modulators due to their age or genotype. For them, our work is not done. We are committed to finding a cure and advancing therapies for every person with CF. | Cystic Fibrosis
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