Cary Grants Best Moments in Arsenic and Old Lace Arsenic and Old Lace is a 1944 American black comedy film directed by Frank Capra and starring Cary Grant. The screenplay by Julius J. Epstein and Philip G. Epstein is based on Joseph Kesselring's 1941 play of the same name. The contract with the play's producers stipulated that the film would not be released until the Broadway run ended. The original planned release date was September 30, 1942. The play was hugely successful, running for three an